The Anti ds DNA Antibody Test plays a vital role in diagnosing and monitoring lupus nephritis, a serious complication of systemic lupus erythematosus (SLE). Lupus nephritis develops when autoimmune inflammation damages the kidneys, which can lead to long-term kidney problems if not detected early. Understanding how this test supports diagnosis helps ensure timely medical intervention. What Is Lupus Nephritis? Lupus nephritis occurs when the immune system attacks kidney tissue, causing inflammation and reduced kidney function. Symptoms may include swelling in the legs or face, foamy urine, high blood pressure, and abnormal kidney test results. Early diagnosis is critical to prevent irreversible damage. Why the Anti ds DNA Antibody Test Matters High anti-dsDNA antibody levels are strongly linked to kidney involvement in lupus. The Anti ds DNA Antibody Test helps identify patients at risk or those with active kidney inflammation. Rising levels often indicate increased immune activity.